This page explains how the body works; it isn't medical advice. If you think you or someone else has asthma, talk to a doctor or nurse.
What causes asthma? The short answer
Nobody knows the exact cause of asthma, and it may be different from person to person.212 What scientists do know is what happens: in asthma, the airways in the lungs are a little swollen and extra sensitive, even on a good day.10 When something sets them off, three things narrow the tubes:210
- the muscle wrapped around each airway tightens,
- the lining inside swells up, and
- the lining makes extra mucus, which clogs the space that's left.
Air then has to squeeze through a narrow gap, which causes wheezing, coughing, shortness of breath and a tight chest.3 Why some people's airways are sensitive in the first place isn't fully known, but genes and surroundings likely play a role: family history, allergies, early chest infections, smoke and pollution.215
What is asthma?
Asthma is a long-term (chronic) condition that affects the airways, the tubes that carry air in and out of your lungs. With asthma, the airways can become inflamed and narrowed at times, which makes it harder for air to flow, especially when you breathe out.1 Symptoms usually come and go, and between flare-ups many people feel completely normal.311
It is very common. About 1 in 13 people in the United States have asthma: roughly 25 million people, including about 4.7 million children (CDC, 2021 data).18 It often starts in childhood, but it can begin at any age.110
How does asthma affect the respiratory system?
Your airways look like an upside-down tree.6 Air goes down the windpipe (trachea), which splits into two bronchi, one for each lung. These branch again and again into tiny bronchioles, each about 1 millimetre across.16
The windpipe and bronchi are held open by stiff rings of cartilage. Bronchioles have no cartilage. Instead, their walls are muscular, and that muscle can change the size of the tube.16 The inside is lined with a moist layer containing cells that make mucus, a sticky film that normally traps dust so it can be swept away.16 Asthma happens in exactly these two places: the muscle and the lining.16
Why a small squeeze makes such a big difference
The width of a tube is the main thing that decides how easily air flows through it.17 And the effect is much bigger than you might expect. For smooth flow, the resistance of a tube depends on its radius raised to the fourth power, so narrowing a tube by only about a sixth (16%) can cut the flow in half.18 Real airways are messier than a physics textbook tube, but the lesson holds: a little squeezing goes a long way.
flow ∝ radius⁴ so 16% narrower ≈ half the flow
How does asthma affect the body? Signs and symptoms
The main symptoms are:311
- Wheezing: a whistling sound when you breathe out
- Coughing, especially at night or early in the morning
- Shortness of breath
- A tight chest
Other conditions can cause these too, but in asthma they tend to follow a pattern: they come and go, get worse with colds, are set off by things like exercise, allergies or cold air, and are often worse at night or in the morning.3 During a bad flare-up (an asthma attack), some people say it feels like trying to breathe through a straw.4
Asthma triggers: why does it flare up today?
A trigger is anything that sets off or worsens symptoms in airways that are already sensitive.2 A calm airway meets a speck of pollen and ignores it. A sensitive airway overreacts to something that is usually harmless and narrows too much.2 Common triggers include:2712
- Allergens: pollen from grass, trees and weeds (the same pollen behind hay fever; see how pollination works), dust mites (microscopic bugs that live in bedding), mould and pet dander (tiny skin flakes from furry pets)
- Infections: colds, flu and other chest infections
- Irritants in the air: cigarette smoke, air pollution, wildfire smoke, strong fumes
- Weather: cold air, sudden temperature changes, thunderstorms
- Exercise, especially in cold, dry air
- Strong emotions, stress, even big laughs
- Some medicines, such as aspirin or ibuprofen in some people
Everyone's triggers are different, and they can change over time.715 Knowing your own triggers and avoiding them where you can is a big part of keeping asthma under control.7
Why do some people get asthma? Genes plus surroundings
Triggers explain a flare-up. They don't explain why someone's airways became sensitive in the first place. That's the real "cause" question, and scientists are still working on it.214 Asthma often begins when the body's defence system reacts strongly to something breathed into the lungs, usually in childhood while that defence system is still taking shape.2 Many things can work together to make that more likely:
- Family history. If a parent has asthma, a child is 3 to 6 times more likely to develop it.9 This is partly genes and partly the home you share.14
- Allergies. Asthma is often a type of allergic reaction, and many people with asthma also have hay fever, eczema or a food allergy.212
- Early chest infections. Viral infections that affect breathing in babies and young children, such as bronchiolitis, are linked to asthma later.212
- Smoke and pollution. Breathing cigarette smoke as a child, a mother smoking during pregnancy, and air pollution all raise the risk.912
- Being born early or with a low birth weight.12
- Weight. Being very overweight raises the risk and can make asthma harder to control.29
None of these is a sure thing. Having someone with asthma in the family doesn't mean you'll get it, and people can get asthma with no family history at all.14
What causes asthma in adults?
Asthma can start for the first time in adulthood, called adult-onset asthma.2 Common reasons include:
- Work exposures such as flour dust, wood dust, spray-paint chemicals or latex (occupational asthma), a common cause of adult-onset asthma.1214
- Hormones: as children more boys than girls have asthma, but after puberty it becomes more common in girls, and some women first develop it around menopause.214
- Smoking and obesity.914
Sometimes childhood asthma fades as the lungs grow, then comes back later in life.10
How is asthma treated? Relievers and preventers
There's no cure for asthma yet, but treatment controls it well enough for most people to live a normal, active life.113 The main treatment is medicine you breathe in through an inhaler, and the two main kinds fix different parts of the problem:13
- Reliever inhalers (often blue) relax the tight muscle around the airways and should ease symptoms within a few minutes.513
- Preventer inhalers contain a steroid medicine and are used every day, even when you feel fine. They reduce the inflammation and sensitivity of the airways, so flare-ups happen less often.13
- Some people use a combination inhaler that does both jobs.11
Doctors also help each person write an asthma action plan: which triggers to avoid, how to spot a flare-up, which medicine to take when, and when to get help.5 Needing a reliever three or more times a week is a sign to check in with a doctor or nurse.13
When is it an emergency? If a reliever inhaler isn't helping, or breathing is still very hard, call your local emergency number (911 in the US, 999 in the UK) straight away.
411
Can you play sports with asthma?
Yes. With treatment, people with asthma should be able to stay active, and warming up and training regularly can help.25 Asthma is actually common among elite athletes, especially in endurance sports like swimming, running and cycling, and many compete at the Olympics on equal terms with everyone else.19
British runner Paula Radcliffe was diagnosed with asthma at about 14 after getting dizzy and breathless in training. She learned to use inhalers and a peak flow meter, and went on to set the women's marathon world record (2:15:25) in 2003. Her message to young people with asthma: "control your asthma and not let it control you."20
Common misconceptions
"Pollen causes asthma." Pollen, dust mites and pet dander are mostly
triggers: they set off airways that are already sensitive. The exact causes are unknown, but genes and surroundings likely play a role.
14
"Asthma just means being out of shape." Asthma is inflammation, muscle squeeze and mucus in the airways. Some of the fittest people on Earth have it.
1019
"If I feel fine, I can skip my preventer." Preventers work over time by calming inflammation, which is why they're taken every day even without symptoms.
13
"People with asthma shouldn't exercise." With good treatment, staying active is encouraged.
25
"Asthma comes from homes being too clean." This idea has been suggested, but there isn't enough evidence to say it causes asthma.
15
"Kids always grow out of it." Symptoms sometimes fade as the lungs grow, but they can come back later in life.
10
FAQ
What are the major causes of asthma?
Nobody knows the exact cause, and it may differ from person to person. A mix of genes and surroundings raises the chance: a parent with asthma, allergies such as hay fever or eczema, chest infections in early childhood, breathing smoke or polluted air, and (in adults) dusts or chemicals at work.
What is the difference between an asthma cause and an asthma trigger?
A cause is the underlying reason someone's airways became sensitive in the first place. A trigger is something that sets off symptoms on a particular day, like pollen, dust mites, pet dander (tiny skin flakes from furry pets), cold air, smoke, a cold or hard exercise.
What are the signs of asthma?
The main signs are wheezing (a whistling sound when you breathe out), coughing (especially at night or early morning), shortness of breath and a tight chest. They tend to come and go. A doctor or nurse can check whether you have asthma, often with a breathing test called spirometry.
Why do people suddenly get asthma as adults?
Asthma can start at any age. Common reasons for adult-onset asthma include dusts or chemicals at work, hormone changes, smoking and being very overweight. Sometimes childhood asthma that faded comes back later.
Does asthma mean your lungs are damaged?
No. Asthma is about sensitive, inflamed airways that narrow at times, and between flare-ups breathing can be completely normal. Asthma that stays poorly controlled for a long time can thicken the airway walls, which is one reason good treatment matters.
Is asthma genetic?
Partly. If a parent has asthma, a child is three to six times more likely to develop it. But it's not a sure thing: many people with a family history never get asthma, and some people get it with no family history at all.
Can you exercise with asthma?
Yes. With the right treatment, people with asthma should be able to stay active. Warming up and using a reliever before exercise (if a doctor advises it) can help. Many Olympic athletes have asthma, including Paula Radcliffe, who held the women's marathon world record from 2003 to 2019.
Sources
- NHLBI (NIH), What Is Asthma?
- NHLBI (NIH), Asthma: Causes and Triggers
- NHLBI (NIH), Asthma Symptoms
- NHLBI (NIH), Asthma Attack
- NHLBI (NIH), Asthma Treatment and Action Plan
- CDC, About Asthma
- CDC, Controlling Asthma (common triggers)
- CDC, Most Recent National Asthma Data
- American Lung Association, What Causes Asthma?
- American Lung Association, What Is Asthma?
- NHS, Asthma
- NHS, Asthma: Causes
- NHS, Asthma: Treatment
- Asthma + Lung UK, What Causes Asthma?
- MedlinePlus (NIH), Asthma
- OpenStax Anatomy & Physiology 2e, 22.1 Organs and Structures of the Respiratory System
- OpenStax Anatomy & Physiology 2e, 22.3 The Process of Breathing
- OpenStax College Physics 2e, 12.4 Viscosity and Laminar Flow; Poiseuille's Law
- Carlsen KH et al., Exercise and asthma: an overview (European Clinical Respiratory Journal)
- Bulletin of the World Health Organization, Paula Radcliffe: elite athlete and clean air advocate